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PHARMACOKINETICS

Multiple species models are available in:

Pharmacokinetics:

• Non-compartmental pharmacokinetics
• Multi-dose Studies
• Intermittent or continuous intravenous infusion
• Bioequivalence and Bioavailability Testing
• Stability studies

Absorption, Distribution, Metabolism, and Excretion (ADME):

• Blood and plasma kinetics
• Mass Balance
• Quantitative Tissue Distribution

Radioisotopes:

• Common radioisotopes, including 14C, 3H, and 125I
• Metabolite profiling and identification using HPLC radiochemical detector
• Certificate of Analysis Development

Other Services:

• High Pressure Liquid Chromatography (HPLC)
• Liquid Scintillation Counting (LSC)
• Mass Spectrophotometer for non-radiolabeled compounds
• Dissection of 11+ ocular (as well as systemic) tissues for pharmacokinetic analysis

Pharmacokinetic Sample Data