The Biological Test Center has been serving the pharmaceutical  and medical device industries with contract laboratory testing since 1980. Our 32,200 square foot, AAALAC-accredited, state-of-the-art  facility is  located in Irvine, California.  The BTC offers a variety of programs and  services, all of which are EPA, USDA, and FDA approved.  Our services include: Biocompatibility testing---USP, NF, ISO 10993, FDA OD G95-1 Endotoxin---Pyrogen/LAL testing Surgery laboratory---HEPA filtered air, EKG, ultrasound, radiography, operating microscope, fluoroscopy---Surgical models, studies, and training Microbiology testing---Sterility, bioburden, B&F, microbial ID, preservative effectiveness, package integrity, and special studies Particulate matter testing---Electronic and microscopic methods (HIAC), particulate ID Ophthalmology---In-vivo studies, surgical evaluations, slit-lamp and fundus examinations, neurodiagnostics, ERG, VEP, specular microscopy, pharmacokinetics, model development, Toxicology---Acute, sub-acute; IV, oral, dermal, topical Pharmacokinetics and Metabolism---In-vivo studies, sample preparation, combustion, counting Drug Discovery--Tests for anxiety, depression, schizophrenia, pain and inflammation, learning and memory, attention deficits, epilepsy, Parkinson's disease, drug dependence and withdrawal Safety Pharmacology--Core battery testing of the central nervous system, cardiovascular system, and respiratory system plus supplemental (Tier II) testing